| Name | Peroxiredoxin-1 | ||
| UniProt ID | PRDX1_HUMAN | ||
| Gene Name | PRDX1 | ||
| Gene ID | 5052 | ||
| Synonyms |
PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2
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| Sequence |
MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG SDTIKPDVQKSKEYFSKQK |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa5052 | ||
| Pfam | PF00322; PF00578; PF02630; PF08534; PF10417 | ||
| Pair Name | Periplocin, Gemcitabine | |||
| Phytochemical | Periplocin | |||
| Drug | Gemcitabine | |||
| Disease Info | [ICD-11: 2C10] | Pancreatic cancer | Investigative | |
| Regulate Info | Down-regulation | Peroxiredoxin-1 | Expression | |
| Result | Periplocin exerts antitumor activity by regulating Nrf2-mediated signaling pathway in gemcitabine-resistant pancreatic cancer cells | |||
