| Name | 3-phosphoinositide-dependent protein kinase 1 | ||
| UniProt ID | PDPK1_HUMAN | ||
| Gene Name | PDPK1 | ||
| Gene ID | 5170 | ||
| Synonyms |
PDPK1, PDK1, PDPK2, PDPK2P, PRO0461
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| Sequence |
MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRP
GAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIK ENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDET CTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARAN SFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYD FPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTA YLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLD SNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTE GPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQ EVWRQRYQSHPDAAVQ |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa5170 | ||
| TTD ID | T08074 | ||
| Pfam | PF00069; PF01636; PF03109; PF06293; PF07714; PF12330; PF14531; PF14593 | ||
| Pair Name | Withaferin A, Oxaliplatin | |||
| Phytochemical Name | Withaferin A | |||
| Anticancer drug Name | Oxaliplatin | |||
| Disease Info | [ICD-11: 2C10.Z] | Pancreatic cancer | Investigative | |
| Regulate Info | Down-regulation | 3-phosphoinositide-dependent protein kinase 1 | Phosphorylation | |
| Result | These results support the notion that combination treatment with oxaliplatin and WA could facilitate development of an effective strategy for PC treatment. | |||
