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  1. General Info
  2. Effects Info
  3. Reference
Molecular Details
01. General Information
Name PRKC apoptosis WT1 regulator protein
UniProt ID PAWR_HUMAN
Gene Name PAWR
Gene ID 5074
Synonyms
PAWR, PAR4, Par-4
Sequence
MATGGYRTSSGLGGSTTDFLEEWKAKREKMRAKQNPPGPAPPGGGSSDAAGKPPAGALGT
PAAAAANELNNNLPGGAPAAPAVPGPGGVNCAVGSAMLTRAAPGPRRSEDEPPAASASAA
PPPQRDEEEPDGVPEKGKSSGPSARKGKGQIEKRKLREKRRSTGVVNIPAAECLDEYEDD
EAGQKERKREDAITQQNTIQNEAVNLLDPGSSYLLQEPPRTVSGRYKSTTSVSEEDVSSR
YSRTDRSGFPRYNRDANVSGTLVSSSTLEKKIEDLEKEVVRERQENLRLVRLMQDKEEMI
GKLKEEIDLLNRDLDDIEDENEQLKQENKTLLKVVGQLTR
Pathway Map MAP LINK
KEGG ID hsa5074
TTD ID T00496
Pfam PF01166; PF05911; PF06785; PF08614; PF08702; PF09055; PF11365; PF14661; PF15898; PF16046; PF20529; PF20537
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 578
Pair Name lambda-Carrageenan Oligosaccharides, Fluorouracil
Phytochemical lambda-Carrageenan Oligosaccharides
Drug Fluorouracil
Disease Info [ICD-11: 2B72] Gastric cancer Investigative
Regulate Info Up-regulation PRKC apoptosis WT1 regulator protein Expression
Result These findings suggested that λ-COS could be used as an immune-modulating agent for chemotherapy.
03. Reference
No. Title Href
1 The Antitumor Potential of λ-Carrageenan Oligosaccharides on Gastric Carcinoma by Immunomodulation. Nutrients. 2023 Apr 24;15(9):2044. doi: 10.3390/nu15092044. Click
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