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  1. General Info
  2. Effects Info
  3. Reference
Drug Interaction Details
01. General Information
Pair Name Naringenin, Cisplatin
Phytochemical Name Naringenin (PubChem CID: 439246 )
Anticancer drug Name Cisplatin (PubChem CID: 5702198 )
Structure of
Phytochemical
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2D MOL 3D MOL
Structure of
Anticancer Drug
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2D MOL 3D MOL
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 449
Pair Name Naringenin, Cisplatin
Disease Info [ICD-11: 2C77] Cervical cancer Investigative
Biological Phenomena Induction-->Blockade of cell cycle in G0/G1 phase
Gene Regulation Down-regulation Expression AKT1 hsa207
In Vitro Model HeLa Human papillomavirus-related cervical adenocarcinoma Homo sapiens (Human) CVCL_0030
Result Effect of naringenin and its combination with cisplatin in cell death, proliferation and invasion of cervical cancer spheroids
03. Reference
No. Title Href
1 Effect of naringenin and its combination with cisplatin in cell death, proliferation and invasion of cervical cancer spheroids. RSC Adv. 2020 Dec 22;11(1):129-141. doi: 10.1039/d0ra07309a. Click
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