| Name | Nuclear receptor subfamily 1 group I member 2 | ||
| UniProt ID | NR1I2_HUMAN | ||
| Gene Name | NR1I2 | ||
| Gene ID | 8856 | ||
| Synonyms |
NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR
|
||
| Sequence |
MEVRPKESWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEG
CKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEE RRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSS GCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLL PHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWE CGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHR VVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPF ATPLMQELFGITGS |
||
| Pathway Map | MAP LINK | ||
| T.C. Number | 9.B.208.1.3 | ||
| KEGG ID | hsa8856 | ||
| TTD ID | T82702 | ||
| Pfam | PF00104; PF00105 | ||
| Pair Name | Epifriedelanol, Doxorubicin | |||
| Phytochemical | Epifriedelanol | |||
| Drug | Doxorubicin | |||
| Disease Info | [ICD-11: 2B33.2] | Chronic myeloid leukemia | Investigative | |
| Regulate Info | Up-regulation | Nuclear receptor subfamily 1 group I member 2 | Expression | |
| Result | The present study demonstrated that Epi could enhance Adr-induced cytotoxicity towards K562/ADM cells accompanied by the down-regulation of P-gp and MRP2. | |||
