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  1. General Info
  2. Effects Info
  3. Reference
Drug Details
01. General Information
Name Miglitol
PubChem CID 441314
Molecular Weight 207.22g/mol
Synonyms

MIGLITOL, 72432-03-2, Glyset, (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol, Bay-m-1099, Miglitolum, Bay m 1099, Miglitol (Glyset), UNII-0V5436JAQW, Seibule, Bay 1099, Miglitolum [Latin], 0V5436JAQW, DTXSID0023323, HSDB 8022, (2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(hydroxymethyl)-3,4,5-piperidinetriol, EINECS 276-661-6, NSC-758702, N-(2-Hydroxyethyl)-1-deoxynojirimycin, CHEMBL1561, CHEBI:6935, DTXCID703323, Diastabol, N-hydroxylethyl-1-deoxynojirimycin, Miglitolum (Latin), NSC 758702, Plumarol, MIGLITOL (MART.), MIGLITOL [MART.], 3,4,5-Piperidinetriol, 1-(2-hydroxyethyl)-2-(hydroxymethyl)-,(2R,3R,4R,5S)-, 3,4,5-Piperidinetriol, 1-(2-hydroxyethyl)-2-(hydroxymethyl)-, (2R-(2alpha,3beta,4alpha,5beta))-, SMR000466381, CAS-72432-03-2, Glyset (TN), Miglitol [USAN:INN:BAN], BAY1099;BAY-m1099, N-(2-Hydroxyethyl)moranoline, N-hydroxyethyl-1-desoxynojirimycin, NCGC00095127-01, N-hydroxyethyl-1-desoxy-nojirimycin, MFCD00867240, SK-983, baym1099, MIGLITOL [USAN], MIGLITOL [INN], MIGLITOL [JAN], MIGLITOL [MI], MIGLITOL [VANDF], 1,5-Dideoxy-1,5-((2-hydroxyethyl)imino)-D-glucitol, MIGLITOL [WHO-DD], 1,5-Dideoxy-1,5-, SCHEMBL22593, MLS000759514, MLS001424128, MLS006011963, BIDD:GT0732, BAY o1099, MIGLITOL [ORANGE BOOK], cid_441314, GTPL4842, Miglitol (JP17/USAN/INN), IBAQFPQHRJAVAV-ULAWRXDQSA-N, HMS2051D05, HMS3713J07, HY-B0481, Tox21_111436, BDBM50242271, AKOS015969689, N-(b-Hydroxyethyl)-1-deoxynojirimycin, Tox21_111436_1, CCG-100920, DB00491, KS-1242, NC00170, NCGC00270540-02, N-(beta-Hydroxyethyl)-1-deoxynojirimycin, M2302, NS00004693, S2589, C07708, C76308, D00625, EN300-119541, AB00639982-06, AB00639982_08, N-hydroxyethyl-1-desoxynojirimycin (BAY o1099), A837526, Q772735, SR-01000759413, SR-01000759413-4, W-104490, BRD-K44779798-001-06-5, Z1269163651, (2R,3R,4R,5S)-1-ethoxy-2-(hydroxymethyl)piperidine-3,4,5-triol, (4R,5R)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol, 1204250-58-7, 3,4,5-PIPERIDINETRIOL, 1-(2-HYDROXYETHYL)-2-(HYDROXYMETHYL)-, (2R-(2.ALPHA.,3.BETA.,4.ALPHA.,5.BETA.))-, 3,4,5-piperidinetriol, 1-(2-hydroxyethyl)-2-(hydroxymethyl)-, (2R-(2alpha,3beta,4alpha, 5beta))-

Drug Type Small molecule
Formula C₈H₁₇NO₅
SMILES C1C(C(C(C(N1CCO)CO)O)O)O
InChI 1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1
InChIKey IBAQFPQHRJAVAV-ULAWRXDQSA-N
CAS Number 72432-03-2
ChEMBL ID CHEMBL1561
ChEBI ID CHEBI:6935
TTD ID D0D0ZD
Drug Bank ID DB00491
KEGG ID C07708
Toxicity Organism Test Type Route(Dose)
rat LD50 intraperitoneal(165 mg/kg)
mouse LD50 intraperitoneal(254 mg/kg)
rat LD50 oral(322 mg/kg)
Structure 2D-img
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2D MOL 3D MOL
02. Combinatorial Therapeutic Effect(s)
Antagonistic Effect
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Reducing Drug Efficacy
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Combination Pair ID: 1069
Pair Name Niacinamide, Miglitol
Partner Name Niacinamide
Result The efficacy of insulin and other antidiabetic agents may be diminished by certain drugs, including atypical antipsychotics, corticosteroids, diuretics, estrogens, gonadotropin-releasing hormone agonists, human growth hormone, phenothiazines, progestins, protease inhibitors, sympathomimetic amines, thyroid hormones, L-asparaginase, alpelisib, copanlisib, danazol, diazoxide, isoniazid, megestrol, omacetaxine, phenytoin, tagraxofusp, temsirolimus, as well as pharmacologic dosages of nicotinic acid and adrenocorticotropic agents. These drugs may interfere with blood glucose control because they can cause hyperglycemia, glucose intolerance, new-onset diabetes mellitus, and/or exacerbation of preexisting diabetes.
03. Reference
No. Title Href
1 DDInter: an online drug-drug interaction database towards improving clinical decision-making and patient safety. Nucleic Acids Res. 2022;50(D1):D1200-D1207. doi:10.1093/nar/gkab880 Click
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