Pair Name | Menadione, Sodium orthovanadate | ||
Phytochemical Name | Menadione (PubChem CID: 4055 ) | ||
Anticancer drug Name | Sodium orthovanadate (PubChem CID: 61671 ) | ||
Structure of Phytochemical |
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2D
MOL
3D
MOL
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Structure of Anticancer Drug |
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2D
MOL
3D
MOL
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Pair Name | Menadione, Sodium orthovanadate | |||
Disease Info | [ICD-11: 2C25] | Lung cancer | Investigative | |
Biological Phenomena | Inhibition-->Cell metastasis | |||
In Vitro Model | A-549 | Lung adenocarcinoma | Homo sapiens (Human) | CVCL_0023 |
Result | Our data guarantee further studies to evaluate the in vivo occurrence of D-IDCs, their implications for invasiveness and metastasis and their sensitivity to anticancer drugs. |
Pair Name | Menadione, Sodium orthovanadate | |||
Disease Info | [ICD-11: 2A00] | Glioblastoma multiforme | Investigative | |
In Vitro Model | DBTRG-05MG | Anaplastic astrocytoma | Homo sapiens (Human) | CVCL_1169 |
Result | Our results indicate that M:SO combination is an attractive alternative for glioma treatment that encourages further study. The neutralizing effects of genistein and DTT reveal a possibility for their use in the minimization of potential M:SO systemic toxicity. |
No. | Title | Href |
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1 | Menadione : sodium orthovanadate combination eliminates and inhibits migration of detached cancer cells. ISRN Pharmacol. 2012;2012:307102. doi: 10.5402/2012/307102. | Click |
2 | Cytotoxic effect of menadione and sodium orthovanadate in combination on human glioma cells. Invest New Drugs. 2012 Aug;30(4):1302-10. doi: 10.1007/s10637-011-9680-y. | Click |