| Name | Matrix metalloproteinase-13 | ||
| UniProt ID | MMP13_HUMAN | ||
| Gene Name | MMP13 | ||
| Gene ID | 4322 | ||
| Synonyms |
MMP13, CLG3, MANDP1, MDST, MMP-13
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| Sequence |
MHPGVLAAFLFLSWTHCRALPLPSGGDEDDLSEEDLQFAERYLRSYYHPTNLAGILKENA
ASSMTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGEYNVFPRTLKWSKMNLTY RIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDG PSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALM FPIYTYTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKHPKTPDKCDPSLSLDAITSLRGET MIFKDRFFWRLHPQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGY DILEGYPKKISELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDYPRLI EEDFPGIGDKVDAVYEKNGYIYFFNGPIQFEYSIWSNRIVRVMPANSILWC |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa4322 | ||
| TTD ID | T34296 | ||
| Pfam | PF00045; PF00413; PF01471; PF13582; PF13583; PF13688; PF16313 | ||
| Pair Name | Paeoniflorin, Talatizidine | |||
| Phytochemical | Paeoniflorin | |||
| Drug | Talatizidine | |||
| Disease Info | [ICD-11: FA20] | Rheumatoid arthritis | Investigative | |
| Regulate Info | Up-regulation | Matrix metalloproteinase-13 | Expression | |
| Result | This study identified PAE and TLT as the main BACs of WTD in alleviating the severity of RA, and also developed a novel combination of PAE and TLT as a promising candidate drug for RA therapy. | |||
