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  1. General Info
  2. Effects Info
  3. Reference
Molecular Details
01. General Information
Name microRNA 155
UniProt ID /
Gene Name MIR155
Gene ID 406947
Synonyms
MIR155, MIRN155, miRNA155, mir-155
Sequence
/
Pathway Map MAP LINK
KEGG ID hsa406947
TTD ID T88483
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 124
Ref_1
Pair Name Epigallocatechin gallate, Fluorouracil
Phytochemical Epigallocatechin gallate
Drug Fluorouracil
Disease Info [ICD-11: 2B91.Z] Colorectal cancer Investigative
Regulate Info Up-regulation microRNA 155 Expression
Result Our data show that EGCG may be act as a novel chemo-sensitizer, and the GRP78/NF-κB/miR-155-5p/MDR1 pathway plays a vital role in EGCG enhancing the sensitivity of colorectal cancer to 5-FU.
03. Reference
No. Title Href
1 (-)-Epigallocatechin Gallate (EGCG) Enhances the Sensitivity of Colorectal Cancer Cells to 5-FU by Inhibiting GRP78/NF-κB/miR-155-5p/MDR1 Pathway. J Agric Food Chem. 2019 Mar 6;67(9):2510-2518. doi: 10.1021/acs.jafc.8b06665. Click
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