InterPAD - DETAILS

Liraglutide, 204656-20-2, NN2211, victoza, NN-2211, Liraglutida, Liraglutidum, NN 2211, Liraglutidum [INN-Latin], Liraglutida [INN-Spanish], UNII-839I73S42A, HSDB 8205, Liraglutide (rDNA origin), NNC 90-1170, CHEMBL4084119, Saxenda, CHEBI:71193, DTXSID60174433, 839I73S42A, NN-9924, NNC-90-1170, N26-(Hexadecanoyl-gamma-glutamyle)-(34-arginine)GLP-1-(7-37)-peptide, Liraglutidum (INN-Latin), Liraglutida (INN-Spanish), N26-(Hexadecanoyl-gamma-glutamyle)-(34-arginine)glucagon-like-peptide-1-(7-37)-peptide, Arg34Lys26-(N-epsilon-(gamma-Glu(N-alpha-hexadecanoyl)))-GLP-1(7-37), N(sup 26)-(Hexadecanoyl-gamma-glutamyle)-(34-arginine)GLP-1-(7-37)-peptide, Liraglutide?, L-Histidyl-L-alanyl-L-a-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-a-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-a-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(1-oxohexadecyl)-L-?-glutamyl]-L-lysyl-L-a-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine, Liraglutide [USAN:INN:BAN:JAN], Liraglutidum (Latin), LIRAGLUTIDE (MART.), GTPL1133, DTXCID6096924, A10BJ02, EX-A2418, BDBM50240819, NN9924, AKOS037435224, AS-56276, FT-0696479, XULTOPHY 100/3.6 COMPONENT LIRAGLUTIDE, LIRAGLUTIDE COMPONENT OF XULTOPHY 100/3.6, ARG(SUP 34)LYS(SUP 26)-(N-epsilon-(gamma-GLU(N-alpha-HEXADECANOYL)))-GLP-1(7-37), N(SUP epsilon26)-(N-HEXADECANOYL-L-gamma-GLUTAMYL)-(34-L-ARGININE)GLUCAGON-LIKE PEPTIDE 1-(7-37)-PEPTIDE, N26-(N-Hexadecanoyl-L-gamma-glutamyl)-(34-L-arginine)glucagon-like peptide 1-(7-37)-peptide

No.	Title	Href
1	DDInter: an online drug-drug interaction database towards improving clinical decision-making and patient safety. Nucleic Acids Res. 2022;50(D1):D1200-D1207. doi:10.1093/nar/gkab880	`Click`

No.

Title

Href

DDInter: an online drug-drug interaction database towards improving clinical decision-making and patient safety. Nucleic Acids Res. 2022;50(D1):D1200-D1207. doi:10.1093/nar/gkab880

Click

Name	Liraglutide
PubChem CID	16134956
Molecular Weight	3751g/mol
Synonyms	Liraglutide, 204656-20-2, NN2211, victoza, NN-2211, Liraglutida, Liraglutidum, NN 2211, Liraglutidum [INN-Latin], Liraglutida [INN-Spanish], UNII-839I73S42A, HSDB 8205, Liraglutide (rDNA origin), NNC 90-1170, CHEMBL4084119, Saxenda, CHEBI:71193, DTXSID60174433, 839I73S42A, NN-9924, NNC-90-1170, N26-(Hexadecanoyl-gamma-glutamyle)-(34-arginine)GLP-1-(7-37)-peptide, Liraglutidum (INN-Latin), Liraglutida (INN-Spanish), N26-(Hexadecanoyl-gamma-glutamyle)-(34-arginine)glucagon-like-peptide-1-(7-37)-peptide, Arg34Lys26-(N-epsilon-(gamma-Glu(N-alpha-hexadecanoyl)))-GLP-1(7-37), N(sup 26)-(Hexadecanoyl-gamma-glutamyle)-(34-arginine)GLP-1-(7-37)-peptide, Liraglutide?, L-Histidyl-L-alanyl-L-a-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-a-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-a-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(1-oxohexadecyl)-L-?-glutamyl]-L-lysyl-L-a-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine, Liraglutide [USAN:INN:BAN:JAN], Liraglutidum (Latin), LIRAGLUTIDE (MART.), GTPL1133, DTXCID6096924, A10BJ02, EX-A2418, BDBM50240819, NN9924, AKOS037435224, AS-56276, FT-0696479, XULTOPHY 100/3.6 COMPONENT LIRAGLUTIDE, LIRAGLUTIDE COMPONENT OF XULTOPHY 100/3.6, ARG(SUP 34)LYS(SUP 26)-(N-epsilon-(gamma-GLU(N-alpha-HEXADECANOYL)))-GLP-1(7-37), N(SUP epsilon26)-(N-HEXADECANOYL-L-gamma-GLUTAMYL)-(34-L-ARGININE)GLUCAGON-LIKE PEPTIDE 1-(7-37)-PEPTIDE, N26-(N-Hexadecanoyl-L-gamma-glutamyl)-(34-L-arginine)glucagon-like peptide 1-(7-37)-peptide
Drug Type	Peptide
Formula	C₁₇₂H₂₆₅N₄₃O₅₁
SMILES	CCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCCC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)O)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CCC(=O)N)NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC5=CC=CC=C5)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CC6=CN=CN6)N)C(=O)O
InChI	1S/C172H265N43O51/c1-18-20-21-22-23-24-25-26-27-28-29-30-37-53-129(224)195-116(170(265)266)59-64-128(223)180-68-41-40-50-111(153(248)199-115(62-67-135(232)233)154(249)204-120(73-100-44-33-31-34-45-100)159(254)214-140(93(11)19-2)167(262)192-97(15)146(241)201-122(76-103-79-183-108-49-39-38-48-106(103)108)157(252)203-118(72-90(5)6)158(253)212-138(91(7)8)165(260)200-110(52-43-70-182-172(177)178)149(244)184-81-130(225)193-109(51-42-69-181-171(175)176)148(243)187-84-137(236)237)196-144(239)95(13)189-143(238)94(12)191-152(247)114(58-63-127(174)222)194-131(226)82-185-151(246)113(61-66-134(230)231)198-155(250)117(71-89(3)4)202-156(251)119(75-102-54-56-105(221)57-55-102)205-162(257)124(85-216)208-164(259)126(87-218)209-166(261)139(92(9)10)213-161(256)123(78-136(234)235)206-163(258)125(86-217)210-169(264)142(99(17)220)215-160(255)121(74-101-46-35-32-36-47-101)207-168(263)141(98(16)219)211-132(227)83-186-150(245)112(60-65-133(228)229)197-145(240)96(14)190-147(242)107(173)77-104-80-179-88-188-104/h31-36,38-39,44-49,54-57,79-80,88-99,107,109-126,138-142,183,216-221H,18-30,37,40-43,50-53,58-78,81-87,173H2,1-17H3,(H2,174,222)(H,179,188)(H,180,223)(H,184,244)(H,185,246)(H,186,245)(H,187,243)(H,189,238)(H,190,242)(H,191,247)(H,192,262)(H,193,225)(H,194,226)(H,195,224)(H,196,239)(H,197,240)(H,198,250)(H,199,248)(H,200,260)(H,201,241)(H,202,251)(H,203,252)(H,204,249)(H,205,257)(H,206,258)(H,207,263)(H,208,259)(H,209,261)(H,210,264)(H,211,227)(H,212,253)(H,213,256)(H,214,254)(H,215,255)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H,265,266)(H4,175,176,181)(H4,177,178,182)/t93-,94-,95-,96-,97-,98+,99+,107-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,138-,139-,140-,141-,142-/m0/s1
InChIKey	YSDQQAXHVYUZIW-QCIJIYAXSA-N
CAS Number	204656-20-2
ChEMBL ID	CHEMBL4084119
ChEBI ID	CHEBI:71193
TTD ID	D03GOI
Drug Bank ID	DB06655
Toxicity	Organism	Test Type	Route(Dose)
	rat	LD50	intraperitoneal(165 mg/kg)
	mouse	LD50	intraperitoneal(254 mg/kg)
	rat	LD50	oral(322 mg/kg)
Structure			Download 2D MOL 3D MOL

Pair Name	Niacinamide, Liraglutide
Partner Name	Niacinamide
Result	The efficacy of insulin and other antidiabetic agents may be diminished by certain drugs, including atypical antipsychotics, corticosteroids, diuretics, estrogens, gonadotropin-releasing hormone agonists, human growth hormone, phenothiazines, progestins, protease inhibitors, sympathomimetic amines, thyroid hormones, L-asparaginase, alpelisib, copanlisib, danazol, diazoxide, isoniazid, megestrol, omacetaxine, phenytoin, tagraxofusp, temsirolimus, as well as pharmacologic dosages of nicotinic acid and adrenocorticotropic agents. These drugs may interfere with blood glucose control because they can cause hyperglycemia, glucose intolerance, new-onset diabetes mellitus, and/or exacerbation of preexisting diabetes.