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  1. General Info
  2. Effects Info
  3. Reference
Molecular Details
01. General Information
Name Prostate-specific antigen
UniProt ID KLK3_HUMAN
Gene Name KLK3
Gene ID 354
Synonyms
KLK3, APS, KLK2A1, PSA, hK3
Sequence
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV
LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD
LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS
NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP
SLYTKVVHYRKWIKDTIVANP
Pathway Map MAP LINK
T.C. Number 8.A.131.1.5; 8.A.131.1.6
KEGG ID hsa354
TTD ID T36935
Pfam PF00089; PF08517; PF09342; PF13365
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 608
Pair Name Noscapine, Paclitaxel
Phytochemical Noscapine
Drug Paclitaxel
Disease Info [ICD-11: 2C82] Prostate cancer Investigative
Regulate Info Down-regulation Prostate-specific antigen Expression
Result This study provides a novel concept of combination treatment of paclitaxel and noscapine to improve efficiency in human prostate cancer treatment.
03. Reference
No. Title Href
1 Synergistic Anticancer Effect of Paclitaxel and Noscapine on Human Prostate Cancer Cell Lines. Iran J Pharm Res. 2017 Fall;16(4):1432-1442. Click
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