Name | Transcription factor JunD | ||
UniProt ID | JUND_HUMAN | ||
Gene Name | JUND | ||
Gene ID | 3727 | ||
Synonyms |
JUND, AP-1
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Sequence |
METPFYGDEALSGLGGGASGSGGSFASPGRLFPGAPPTAAAGSMMKKDALTLSLSEQVAA
ALKPAAAPPPTPLRADGAPSAAPPDGLLASPDLGLLKLASPELERLIIQSNGLVTTTPTS SQFLYPKVAASEEQEFAEGFVKALEDLHKQNQLGAGAAAAAAAAAAGGPSGTATGSAPPG ELAPAAAAPEAPVYANLSSYAGGAGGAGGAATVAFAAEPVPFPPPPPPGALGPPRLAALK DEPQTVPDVPSFGESPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKV KTLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQHQVPAY |
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Pathway Map | MAP LINK | ||
KEGG ID | hsa3727 | ||
Pfam | PF00170; PF01166; PF03131; PF03957; PF04012; PF05266; PF05300; PF06005; PF07716; PF11932; PF15186; PF19579 |
Pair Name | Bisdemethoxycucurmin, Icotinib | |||
Phytochemical | Bisdemethoxycucurmin | |||
Drug | Icotinib | |||
Disease Info | [ICD-11: 2C25] | Lung cancer | Investigative | |
Regulate Info | Up-regulation | Transcription factor JunD | Expression | |
Result | Our data indicate that BMDC has the potential to improve the treatment of primary EGFR-TKI resistant NISCLC that cannot be controlled with single-target agent, such as icotinib. |