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  1. General Info
  2. Effects Info
  3. Reference
Molecular Details
01. General Information
Name Interleukin-19
UniProt ID IL19_HUMAN
Gene Name IL19
Gene ID 29949
Synonyms
IL19, IL-10C, MDA1, NG.1, ZMDA1
Sequence
MKLQCVSLWLLGTILILCSVDNHGLRRCLISTDMHHIEESFQEIKRAIQAKDTFPNVTIL
STLETLQIIKPLDVCCVTKNLLAFYVDRVFKDHQEPNPKILRKISSIANSFLYMQKTLRQ
CQEQRQCHCRQEATNATRVIHDNYDQLEVHAAAIKSLGELDVFLAWINKNHEVMFSA
Pathway Map MAP LINK
KEGG ID hsa29949
TTD ID T44584
Pfam PF00726; PF13012
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Decreasing Drug Toxicity
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Combination Pair ID: 760
Pair Name Aloin, Doxorubicin
Phytochemical Name Aloin
Anticancer drug Name Doxorubicin
Disease Info [ICD-11: 2A00-2F9Z] Solid tumour or cancer Investigative
Regulate Info Down-regulation Interleukin-19 Expression
Result Our results highlight the necessity to further investigate the chemopreventive effects of aloin against other chemotherapeutic agents.
03. Reference
No. Title Href
1 Aloin alleviates doxorubicin-induced cardiotoxicity in rats by abrogating oxidative stress and pro-inflammatory cytokinesAloin alleviates doxorubicin-induced cardiotoxicity in rats by abrogating oxidative stress and pro-inflammatory cytokines. Cancer Chemother Pharmacol. 2020 Sep;86(3):419-426. doi: 10.1007/s00280-020-04125-w. Click
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