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  1. General Info
  2. Effects Info
  3. Reference
Drug Details
01. General Information
Name Hydroxyl-chloroquine
Drug Type Small molecule
Toxicity Organism Test Type Route(Dose)
Structure 2D-img
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2D MOL 3D MOL
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 858
Ref_1
Pair Name Cianidanol, Hydroxyl-chloroquine
Partner Name Cianidanol
Disease Info [ICD-11: 2C25.Z] Lung cancer Investigative
Biological Phenomena Induction-->Autophagy
Gene Regulation Up-regulation Expression MAP1LC3B hsa81631
In Vitro Model A-549 Lung adenocarcinoma Homo sapiens (Human) CVCL_0023
Result These findings suggest that the potential utility of GTE in lung cancer therapy may lie in its synergistic combinations with drugs or small molecules that target autophagy, rather than as a standalone therapy.
03. Reference
No. Title Href
1 Green tea extract and hydroxyl-chloroquine combination enhances apoptosis in A549 non-small cell lung cancer cells. Bioinformation. 2023 Aug 31;19(8):860-865. doi: 10.6026/97320630019860. Click
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