Name | Heterogeneous nuclear ribonucleoproteins A2/B1 | ||
UniProt ID | ROA2_HUMAN | ||
Gene Name | HNRNPA2B1 | ||
Gene ID | 3181 | ||
Synonyms |
HNRNPA2B1, HNRNPA2, HNRNPB1, HNRPA2, HNRPA2B1, HNRPB1, IBMPFD2, OPMD2, RNPA2, SNRPB1
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Sequence |
MEKTLETVPLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKR
SRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIK EDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGH NAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGF GDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNY NDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGRSRY |
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Pathway Map | MAP LINK | ||
KEGG ID | hsa3181 | ||
TTD ID | T29095 | ||
Pfam | PF00076; PF11627; PF16367 |
Pair Name | Kaempferol, Fluorouracil | |||
Phytochemical | Kaempferol | |||
Drug | Fluorouracil | |||
Disease Info | [ICD-11: 2B91] | Colorectal cancer | Investigative | |
Regulate Info | Down-regulation | Heterogeneous nuclear ribonucleoproteins A2/B1 | Expression | |
Result | Our data suggest that kaempferol may play an important role in overcoming resistance to 5-Fu therapy by regulating the miR-326-hnRNPA1/A2/PTBP1-PKM2 axis. |