| Name | Heterogeneous nuclear ribonucleoprotein A1 | ||
| UniProt ID | ROA1_HUMAN | ||
| Gene Name | HNRNPA1 | ||
| Gene ID | 3178 | ||
| Synonyms |
HNRNPA1, ALS19, ALS20, HNRPA1, HNRPA1L3, IBMPFD3, MPD3, UP_1, hnRNP_A1, hnRNP-A1
|
||
| Sequence |
MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFV
TYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHH LRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKA LSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGS GDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGG GSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGS SSSSSYGSGRRF |
||
| Pathway Map | MAP LINK | ||
| KEGG ID | hsa3178 | ||
| TTD ID | T12052 | ||
| Pfam | PF00076; PF11627; PF14605; PF16367 | ||
| Pair Name | Kaempferol, Fluorouracil | |||
| Phytochemical | Kaempferol | |||
| Drug | Fluorouracil | |||
| Disease Info | [ICD-11: 2B91.Z] | Colorectal cancer | Investigative | |
| Regulate Info | Down-regulation | Heterogeneous nuclear ribonucleoprotein A1 | Expression | |
| Result | Our data suggest that kaempferol may play an important role in overcoming resistance to 5-Fu therapy by regulating the miR-326-hnRNPA1/A2/PTBP1-PKM2 axis. | |||
