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  1. General Info
  2. Effects Info
  3. Reference
Molecular Details
01. General Information
Name Hyaluronan-binding protein 2
UniProt ID HABP2_HUMAN
Gene Name HABP2
Gene ID 3026
Synonyms
HABP2, FSAP, HABP, HGFAL, NMTC5, PHBP
Sequence
MFARMSDLHVLLLMALVGKTACGFSLMSLLESLDPDWTPDQYDYSYEDYNQEENTSSTLT
HAENPDWYYTEDQADPCQPNPCEHGGDCLVHGSTFTCSCLAPFSGNKCQKVQNTCKDNPC
GRGQCLITQSPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGATCSRHKRRSKFTCACPD
QFKGKFCEIGSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGI
GEHNFCRNPDADEKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDS
CGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTA
AHCTDIKTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPV
DGHCALESKYVKTVCLPDGSFPSGSECHISGWGVTETGKGSRQLLDAKVKLIANTLCNSR
QLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGKRPGVY
TQVTKFLNWIKATIKSESGF
Pathway Map MAP LINK
KEGG ID hsa3026
Pfam PF00008; PF00051; PF00089; PF09342; PF13365
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 520
Pair Name Niacinamide, Gemcitabine
Phytochemical Niacinamide
Drug Gemcitabine
Disease Info [ICD-11: 2C10] Pancreatic cancer Investigative
Regulate Info Down-regulation Hyaluronan-binding protein 2 Expression
Result This study highlights the potential of NAM+GEM as immunotherapy for advanced pancreatic cancer.
03. Reference
No. Title Href
1 Nicotinamide combined with gemcitabine is an immunomodulatory therapy that restrains pancreatic cancer in mice. J Immunother Cancer. 2020 Nov;8(2):e001250. doi: 10.1136/jitc-2020-001250. Click
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