| Name | Alanine aminotransferase 1 | ||
| UniProt ID | ALAT1_HUMAN | ||
| Gene Name | GPT | ||
| Gene ID | 2875 | ||
| Synonyms |
GPT, AAT1, ALT, ALT1, GPT1, SGPT
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| Sequence |
MASSTGDRSQAVRHGLRAKVLTLDGMNPRVRRVEYAVRGPIVQRALELEQELRQGVKKPF
TEVIRANIGDAQAMGQRPITFLRQVLALCVNPDLLSSPNFPDDAKKRAERILQACGGHSL GAYSVSSGIQLIREDVARYIERRDGGIPADPNNVFLSTGASDAIVTVLKLLVAGEGHTRT GVLIPIPQYPLYSATLAELGAVQVDYYLDEERAWALDVAELHRALGQARDHCRPRALCVI NPGNPTGQVQTRECIEAVIRFAFEERLFLLADEVYQDNVYAAGSQFHSFKKVLMEMGPPY AGQQELASFHSTSKGYMGECGFRGGYVEVVNMDAAVQQQMLKLMSVRLCPPVPGQALLDL VVSPPAPTDPSFAQFQAEKQAVLAELAAKAKLTEQVFNEAPGISCNPVQGAMYSFPRVQL PPRAVERAQELGLAPDMFFCLRLLEETGICVVPGSGFGQREGTYHFRMTILPPLEKLRLL LEKLSRFHAKFTLEYS |
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| Pathway Map | MAP LINK | ||
| T.C. Number | 2.A.7.9.2; 2.A.7.9.6 | ||
| KEGG ID | hsa2875 | ||
| Pfam | PF00155 | ||
| Pair Name | Chlorogenic acid, Methotrexate | |||
| Phytochemical Name | Chlorogenic acid | |||
| Anticancer drug Name | Methotrexate | |||
| Disease Info | [ICD-11: 2B33.4] | Leukemia | Investigative | |
| Regulate Info | Down-regulation | Alanine aminotransferase 1 | Expression | |
| Result | These results imply that CGA has perfective effect against MTX-induced liver injury. Hence CGA supplementation might be helpful in abrogation of MTX toxicity. | |||
