Name | Glycerophosphodiester phosphodiesterase 1 | ||
UniProt ID | GDE1_HUMAN | ||
Gene Name | GDE1 | ||
Gene ID | 51573 | ||
Synonyms |
GDE1, 363E6.2, MIR16
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Sequence |
MWLWEDQGGLLGPFSFLLLVLLLVTRSPVNACLLTGSLFVLLRVFSFEPVPSCRALQVLK
PRDRISAIAHRGGSHDAPENTLAAIRQAAKNGATGVELDIEFTSDGIPVLMHDNTVDRTT DGTGRLCDLTFEQIRKLNPAANHRLRNDFPDEKIPTLREAVAECLNHNLTIFFDVKGHAH KATEALKKMYMEFPQLYNNSVVCSFLPEVIYKMRQTDRDVITALTHRPWSLSHTGDGKPR YDTFWKHFIFVMMDILLDWSMHNILWYLCGISAFLMQKDFVSPAYLKKWSAKGIQVVGWT VNTFDEKSYYESHLGSSYITDSMVEDCEPHF |
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Pathway Map | MAP LINK | ||
KEGG ID | hsa51573 | ||
Pfam | PF03009 |
Pair Name | Oleuropein, Cisplatin | |||
Phytochemical | Oleuropein | |||
Drug | Cisplatin | |||
Disease Info | [ICD-11: 2C73] | Ovarian cancer | Investigative | |
Regulate Info | Up-regulation | Glycerophosphodiester phosphodiesterase 1 | Expression | |
Result | These data revealed that oleuropein regulated the expression of the above-mentioned miRNAs in ovarian cancer cells, which potentially resulted in apoptosis induction, cell proliferation inhibition, and cisplatin resistance decline in ovarian cancer cells. To confirm the results of this study, it is suggested that similar experiments be performed in animal models of ovarian cancer. |