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  1. General Info
  2. Effects Info
  3. Reference
Molecular Details
01. General Information
Name DnaJ homolog subfamily B member 4
UniProt ID DNJB4_HUMAN
Gene Name DNAJB4
Gene ID 11080
Synonyms
DNAJB4, CMYP21, DNAJW, DjB4, HLJ1
Sequence
MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKK
REIYDQFGEEGLKGGAGGTDGQGGTFRYTFHGDPHATFAAFFGGSNPFEIFFGRRMGGGR
DSEEMEIDGDPFSAFGFSMNGYPRDRNSVGPSRLKQDPPVIHELRVSLEEIYSGCTKRMK
ISRKRLNADGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFIIKDKDH
PKFKRDGSNIIYTAKISLREALCGCSINVPTLDGRNIPMSVNDIVKPGMRRRIIGYGLPF
PKNPDQRGDLLIEFEVSFPDTISSSSKEVLRKHLPAS
Pathway Map MAP LINK
KEGG ID hsa11080
Pfam PF00226; PF01556
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 499
Pair Name Bisdemethoxycucurmin, Icotinib
Phytochemical Bisdemethoxycucurmin
Drug Icotinib
Disease Info [ICD-11: 2C25] Lung cancer Investigative
Regulate Info Up-regulation DnaJ homolog subfamily B member 4 Expression
Result Our data indicate that BMDC has the potential to improve the treatment of primary EGFR-TKI resistant NISCLC that cannot be controlled with single-target agent, such as icotinib.
03. Reference
No. Title Href
1 Our data indicate that BMDC has the potential to improve the treatment of primary EGFR-TKI resistant NISCLC that cannot be controlled with single-target agent, such as icotinib. Click
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