Name | DnaJ homolog subfamily B member 4 | ||
UniProt ID | DNJB4_HUMAN | ||
Gene Name | DNAJB4 | ||
Gene ID | 11080 | ||
Synonyms |
DNAJB4, CMYP21, DNAJW, DjB4, HLJ1
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Sequence |
MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKK
REIYDQFGEEGLKGGAGGTDGQGGTFRYTFHGDPHATFAAFFGGSNPFEIFFGRRMGGGR DSEEMEIDGDPFSAFGFSMNGYPRDRNSVGPSRLKQDPPVIHELRVSLEEIYSGCTKRMK ISRKRLNADGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFIIKDKDH PKFKRDGSNIIYTAKISLREALCGCSINVPTLDGRNIPMSVNDIVKPGMRRRIIGYGLPF PKNPDQRGDLLIEFEVSFPDTISSSSKEVLRKHLPAS |
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Pathway Map | MAP LINK | ||
KEGG ID | hsa11080 | ||
Pfam | PF00226; PF01556 |
Pair Name | Bisdemethoxycucurmin, Icotinib | |||
Phytochemical | Bisdemethoxycucurmin | |||
Drug | Icotinib | |||
Disease Info | [ICD-11: 2C25] | Lung cancer | Investigative | |
Regulate Info | Up-regulation | DnaJ homolog subfamily B member 4 | Expression | |
Result | Our data indicate that BMDC has the potential to improve the treatment of primary EGFR-TKI resistant NISCLC that cannot be controlled with single-target agent, such as icotinib. |