| Name | ATP-dependent RNA helicase DDX3X | ||
| UniProt ID | DDX3X_HUMAN | ||
| Gene Name | DDX3X | ||
| Gene ID | 1654 | ||
| Synonyms |
DDX3X, CAP-Rf, DBX, DDX14, DDX3, HLP2, MRX102, MRXSSB
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| Sequence |
MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGW
SSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFE RGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIE SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS QIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV WVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR EEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGL ATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGAR DYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGYGGNYNSQGVDWW GN |
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| Pathway Map | MAP LINK | ||
| T.C. Number | 1.I.1.1.3 | ||
| KEGG ID | hsa1654 | ||
| Pfam | PF00270; PF00271; PF04851; PF06862 | ||
| Pair Name | Curcumin, TNF-related apoptosis inducing ligand | |||
| Phytochemical | Curcumin | |||
| Drug | TNF-related apoptosis inducing ligand | |||
| Disease Info | [ICD-11: 2C17] | Hepatocellular carcinoma | Investigative | |
| Regulate Info | Down-regulation | ATP-dependent RNA helicase DDX3X | Expression | |
| Result | The present study demonstrates the potential of using curcumin in combination with TRAIL to yield better TRAIL therapy outcomes in TRAIL-resistant CCA. | |||
| No. | Title | Href |
|---|---|---|
| 1 | Potentiation of TRAIL-Induced Apoptosis in TRAIL-Resistant Cholangiocarcinoma Cells by Curcumin through the Induction of DR5 Membrane Localization and Disruption of the Anti-Apoptotic Complex DR5/DDX3/GSK3β. Asian Pac J Cancer Prev. 2023 Feb 1;24(2):425-434. doi: 10.31557/APJCP.2023.24.2.425. | Click |
