Name | dCTP pyrophosphatase 1 | ||
UniProt ID | DCTP1_HUMAN | ||
Gene Name | DCTPP1 | ||
Gene ID | 79077 | ||
Synonyms |
DCTPP1, CDA03, RS21C6, XTP3TPA
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Sequence |
MSVAGGEIRGDTGGEDTAAPGRFSFSPEPTLEDIRRLHAEFAAERDWEQFHQPRNLLLAL
VGEVGELAELFQWKTDGEPGPQGWSPRERAALQEELSDVLIYLVALAARCRVDLPLAVLS KMDINRRRYPAHLARSSSRKYTELPHGAISEDQAVGPADIPCDSTGQTST |
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Pathway Map | MAP LINK | ||
KEGG ID | hsa79077 | ||
Pfam | PF03819; PF08761; PF12643 |
Pair Name | Hypericin, Gemcitabine | |||
Phytochemical | Hypericin | |||
Drug | Gemcitabine | |||
Disease Info | [ICD-11: 2C10] | Pancreatic cancer | Investigative | |
Regulate Info | Down-regulation | dCTP pyrophosphatase 1 | Expression | |
Result | We demonstrated that Gem combined HY-PDT could inhibit the proliferation of Capan-2 cells and induce cell apoptosis. HY-PDT combined with Gem had a great potential on pancreatic cancer treatment clinically. |