InterPAD - DETAILS

chlorpropamide, 94-20-2, Chloropropamide, Diabinese, Chlorpropamid, Diabenese, Glucamide, Meldian, Chlorodiabina, Chloronase, Diabeneza, Diabetoral, Adiaben, Catanil, Diabaril, Dynalase, Insulase, Melitase, Diabechlor, Diabenal, Mellinese, Millinese, Asucrol, Glisema, Oradian, Diabet-Pages, Diamel Ex, Prodiaben, 4-chloro-N-(propylcarbamoyl)benzenesulfonamide, 1-(4-Chlorophenylsulfonyl)-3-propylurea, Chlorpropamidum, Clorpropamida, Clorpropamide, Diabexan, 1-(p-Chlorobenzenesulfonyl)-3-propylurea, 1-Propyl-3-(p-chlorobenzenesulfonyl)urea, N-(4-Chlorophenylsulfonyl)-N'-propylurea, N-(p-Chlorobenzenesulfonyl)-N'-propylurea, N-Propyl-N'-(p-chlorobenzenesulfonyl)urea, 1-(4-chlorophenyl)sulfonyl-3-propylurea, 1-(p-Chlorophenylsulfonyl)-3-propylurea, 4-Chloro-N-((propylamino)carbonyl)benzenesulfonamide, 1-p-Chlorophenyl-3-(propylsulfonyl)urea, NCI-C01752, n-Propyl-N'-p-chlorophenylsulfonylcarbamide, 1-[(4-chlorobenzene)sulfonyl]-3-propylurea, 4-chloro-N-[(propylamino)carbonyl]benzenesulfonamide, Benzenesulfonamide, 4-chloro-N-((propylamino)carbonyl)-, WTM2C3IL2X, N-Propyl-N'-p-chlorphenylsulfonylcarbamide, 1-((p-Chlorophenyl)sulfonyl)-3-propylurea, 4-Chloro-4-((propylamino)carbonyl)benzenesulfonamide, P 607, NSC 44634, NSC-44634, U-9818, NSC-626720, CHEBI:3650, 1-(4-chlorobenzenesulfonyl)-3-propylurea, DTXSID9020322, Benzenesulfonamide, 4-chloro-N-[(propylamino)carbonyl]-, Clorpropamid, MFCD00079004, Urea, 1-((p-chlorophenyl)sulfonyl)-3-propyl-, CHEMBL498, DTXCID30322, MLS000028395, Bioglumin, Insogen, NSC44634, NSC626720, CAS-94-20-2, NCGC00015216-11, Chlorporpamide, SMR000058364, Clorpropamide [DCIT], chlorpropamide, alpha-form, Clorpropamide [Italian], Urea, 1-[(p-chlorophenyl)sulfonyl]-3-propyl-, chlorpropamide, epsilon-form, chlorpropamide, epsilon`-form, CHLORPROPAMIDE (MART.), CHLORPROPAMIDE [MART.], CHLORPROPAMIDE (USP-RS), CHLORPROPAMIDE [USP-RS], Chlorpropamidum [INN-Latin], Clorpropamida [INN-Spanish], CHLORPROPAMIDE (EP IMPURITY), CHLORPROPAMIDE [EP IMPURITY], CHLORPROPAMIDE (USP MONOGRAPH), CHLORPROPAMIDE [USP MONOGRAPH], Diabinese (TN), CCRIS 155, 1-(p-Chlorobenzensulfonyl)-3-propylurea, HSDB 2051, 4-chloro-n-(propylaminocarbonyl)benzenesulfonamide, SR-01000000060, 4-chloro-N-((propylaminocarbonyl)benzenesulfonamide, EINECS 202-314-5, UNII-WTM2C3IL2X, U-3818, NSC 626720, BRN 2218363, Diabinase, Urea, 1-((p-chloropenyl)sulfonyl)-3-propyl-, Prestwick_684, Chlorpropamide [USP:INN:BAN:JAN], Spectrum_000144, 1-(4-chlorophenyl)sulfonyl-3-propyl-urea, Opera_ID_359, Prestwick0_000323, Prestwick1_000323, Prestwick2_000323, Prestwick3_000323, Spectrum2_000089, Spectrum3_000347, Spectrum4_000284, Spectrum5_000719, WLN: GR DSWMVM3, Lopac-C-1290, chlorpropamide, delta-form, 1-(4-chloro-benzenesulfonyl)-3-n-propyl-urea, C 1290, CHLORPROPAMIDE [MI], CHLORPROPAMIDE [INN], CHLORPROPAMIDE [JAN], Lopac0_000229, SCHEMBL23947, BSPBio_000325, BSPBio_002013, CHLORPROPAMIDE [HSDB], KBioGR_000808, KBioGR_002273, KBioSS_000624, KBioSS_002274, MLS001148665, CHLORPROPAMIDE [VANDF], DivK1c_000513, SPECTRUM1500185, SPBio_000018, SPBio_002246, BPBio1_000359, GTPL6801, CHLORPROPAMIDE [WHO-DD], HMS501J15, KBio1_000513, KBio2_000624, KBio2_002273, KBio2_003192, KBio2_004841, KBio2_005760, KBio2_007409, KBio3_001233, KBio3_002753, Chlorpropamide (JP17/USP/INN), cMAP_000007, NINDS_000513, HMS1569A07, HMS1920M05, HMS2091E08, HMS2096A07, HMS2233L19, HMS3259A17, HMS3260N19, HMS3373D09, HMS3428C03, HMS3652L03, HMS3713A07, Pharmakon1600-01500185, BCP09162, HY-B1429, CHLORPROPAMIDE [ORANGE BOOK], Tox21_110102, Tox21_201391, Tox21_302789, Tox21_500229, AC8695, BDBM50344965, CCG-38905, NSC756690, NSC813219, s4166, STK857458, AKOS001482739, Tox21_110102_1, CS-4917, DB00672, KS-5316, LP00229, NC00503, NSC-756690, NSC-813219, SDCCGSBI-0050217.P005, IDI1_000513, MRF-0000539, NCGC00015216-01, NCGC00015216-02, NCGC00015216-03, NCGC00015216-04, NCGC00015216-05, NCGC00015216-06, NCGC00015216-07, NCGC00015216-08, NCGC00015216-09, NCGC00015216-10, NCGC00015216-12, NCGC00015216-13, NCGC00015216-14, NCGC00015216-17, NCGC00015216-18, NCGC00015216-23, NCGC00021451-03, NCGC00021451-04, NCGC00021451-05, NCGC00021451-06, NCGC00021451-07, NCGC00021451-08, NCGC00256414-01, NCGC00258942-01, NCGC00260914-01, SY052508, SBI-0050217.P004, AB00051944, C1220, Chlorpropamide, analytical standard, >=97%, EU-0100229, NS00005378, P-607, SW196839-3, D00271, U 9818, Urea, 1-propyl-3-(p-chloro-benzenesulfonyl)-, AB00051944_16, AB00051944_17, EN300-7388134, Q1075324, SR-01000000060-2, SR-01000000060-4, SR-01000000060-6, W-100205, 4-Chloro-N-[(propylamino)-carbonyl]benzenesulfonamide, BRD-K97746869-001-05-6, BRD-K97746869-001-15-5, Z276509110, 1-Chloro-4-(([(propylamino)carbonyl]amino)sulfonyl)benzene #, Chlorpropamide, European Pharmacopoeia (EP) Reference Standard, Chlorpropamide, United States Pharmacopeia (USP) Reference Standard, Chlorpropamide, Pharmaceutical Secondary Standard; Certified Reference Material

Name	Chlorpropamide
PubChem CID	2727
Molecular Weight	276.74g/mol
Synonyms	chlorpropamide, 94-20-2, Chloropropamide, Diabinese, Chlorpropamid, Diabenese, Glucamide, Meldian, Chlorodiabina, Chloronase, Diabeneza, Diabetoral, Adiaben, Catanil, Diabaril, Dynalase, Insulase, Melitase, Diabechlor, Diabenal, Mellinese, Millinese, Asucrol, Glisema, Oradian, Diabet-Pages, Diamel Ex, Prodiaben, 4-chloro-N-(propylcarbamoyl)benzenesulfonamide, 1-(4-Chlorophenylsulfonyl)-3-propylurea, Chlorpropamidum, Clorpropamida, Clorpropamide, Diabexan, 1-(p-Chlorobenzenesulfonyl)-3-propylurea, 1-Propyl-3-(p-chlorobenzenesulfonyl)urea, N-(4-Chlorophenylsulfonyl)-N'-propylurea, N-(p-Chlorobenzenesulfonyl)-N'-propylurea, N-Propyl-N'-(p-chlorobenzenesulfonyl)urea, 1-(4-chlorophenyl)sulfonyl-3-propylurea, 1-(p-Chlorophenylsulfonyl)-3-propylurea, 4-Chloro-N-((propylamino)carbonyl)benzenesulfonamide, 1-p-Chlorophenyl-3-(propylsulfonyl)urea, NCI-C01752, n-Propyl-N'-p-chlorophenylsulfonylcarbamide, 1-[(4-chlorobenzene)sulfonyl]-3-propylurea, 4-chloro-N-[(propylamino)carbonyl]benzenesulfonamide, Benzenesulfonamide, 4-chloro-N-((propylamino)carbonyl)-, WTM2C3IL2X, N-Propyl-N'-p-chlorphenylsulfonylcarbamide, 1-((p-Chlorophenyl)sulfonyl)-3-propylurea, 4-Chloro-4-((propylamino)carbonyl)benzenesulfonamide, P 607, NSC 44634, NSC-44634, U-9818, NSC-626720, CHEBI:3650, 1-(4-chlorobenzenesulfonyl)-3-propylurea, DTXSID9020322, Benzenesulfonamide, 4-chloro-N-[(propylamino)carbonyl]-, Clorpropamid, MFCD00079004, Urea, 1-((p-chlorophenyl)sulfonyl)-3-propyl-, CHEMBL498, DTXCID30322, MLS000028395, Bioglumin, Insogen, NSC44634, NSC626720, CAS-94-20-2, NCGC00015216-11, Chlorporpamide, SMR000058364, Clorpropamide [DCIT], chlorpropamide, alpha-form, Clorpropamide [Italian], Urea, 1-[(p-chlorophenyl)sulfonyl]-3-propyl-, chlorpropamide, epsilon-form, chlorpropamide, epsilon`-form, CHLORPROPAMIDE (MART.), CHLORPROPAMIDE [MART.], CHLORPROPAMIDE (USP-RS), CHLORPROPAMIDE [USP-RS], Chlorpropamidum [INN-Latin], Clorpropamida [INN-Spanish], CHLORPROPAMIDE (EP IMPURITY), CHLORPROPAMIDE [EP IMPURITY], CHLORPROPAMIDE (USP MONOGRAPH), CHLORPROPAMIDE [USP MONOGRAPH], Diabinese (TN), CCRIS 155, 1-(p-Chlorobenzensulfonyl)-3-propylurea, HSDB 2051, 4-chloro-n-(propylaminocarbonyl)benzenesulfonamide, SR-01000000060, 4-chloro-N-((propylaminocarbonyl)benzenesulfonamide, EINECS 202-314-5, UNII-WTM2C3IL2X, U-3818, NSC 626720, BRN 2218363, Diabinase, Urea, 1-((p-chloropenyl)sulfonyl)-3-propyl-, Prestwick_684, Chlorpropamide [USP:INN:BAN:JAN], Spectrum_000144, 1-(4-chlorophenyl)sulfonyl-3-propyl-urea, Opera_ID_359, Prestwick0_000323, Prestwick1_000323, Prestwick2_000323, Prestwick3_000323, Spectrum2_000089, Spectrum3_000347, Spectrum4_000284, Spectrum5_000719, WLN: GR DSWMVM3, Lopac-C-1290, chlorpropamide, delta-form, 1-(4-chloro-benzenesulfonyl)-3-n-propyl-urea, C 1290, CHLORPROPAMIDE [MI], CHLORPROPAMIDE [INN], CHLORPROPAMIDE [JAN], Lopac0_000229, SCHEMBL23947, BSPBio_000325, BSPBio_002013, CHLORPROPAMIDE [HSDB], KBioGR_000808, KBioGR_002273, KBioSS_000624, KBioSS_002274, MLS001148665, CHLORPROPAMIDE [VANDF], DivK1c_000513, SPECTRUM1500185, SPBio_000018, SPBio_002246, BPBio1_000359, GTPL6801, CHLORPROPAMIDE [WHO-DD], HMS501J15, KBio1_000513, KBio2_000624, KBio2_002273, KBio2_003192, KBio2_004841, KBio2_005760, KBio2_007409, KBio3_001233, KBio3_002753, Chlorpropamide (JP17/USP/INN), cMAP_000007, NINDS_000513, HMS1569A07, HMS1920M05, HMS2091E08, HMS2096A07, HMS2233L19, HMS3259A17, HMS3260N19, HMS3373D09, HMS3428C03, HMS3652L03, HMS3713A07, Pharmakon1600-01500185, BCP09162, HY-B1429, CHLORPROPAMIDE [ORANGE BOOK], Tox21_110102, Tox21_201391, Tox21_302789, Tox21_500229, AC8695, BDBM50344965, CCG-38905, NSC756690, NSC813219, s4166, STK857458, AKOS001482739, Tox21_110102_1, CS-4917, DB00672, KS-5316, LP00229, NC00503, NSC-756690, NSC-813219, SDCCGSBI-0050217.P005, IDI1_000513, MRF-0000539, NCGC00015216-01, NCGC00015216-02, NCGC00015216-03, NCGC00015216-04, NCGC00015216-05, NCGC00015216-06, NCGC00015216-07, NCGC00015216-08, NCGC00015216-09, NCGC00015216-10, NCGC00015216-12, NCGC00015216-13, NCGC00015216-14, NCGC00015216-17, NCGC00015216-18, NCGC00015216-23, NCGC00021451-03, NCGC00021451-04, NCGC00021451-05, NCGC00021451-06, NCGC00021451-07, NCGC00021451-08, NCGC00256414-01, NCGC00258942-01, NCGC00260914-01, SY052508, SBI-0050217.P004, AB00051944, C1220, Chlorpropamide, analytical standard, >=97%, EU-0100229, NS00005378, P-607, SW196839-3, D00271, U 9818, Urea, 1-propyl-3-(p-chloro-benzenesulfonyl)-, AB00051944_16, AB00051944_17, EN300-7388134, Q1075324, SR-01000000060-2, SR-01000000060-4, SR-01000000060-6, W-100205, 4-Chloro-N-[(propylamino)-carbonyl]benzenesulfonamide, BRD-K97746869-001-05-6, BRD-K97746869-001-15-5, Z276509110, 1-Chloro-4-(([(propylamino)carbonyl]amino)sulfonyl)benzene #, Chlorpropamide, European Pharmacopoeia (EP) Reference Standard, Chlorpropamide, United States Pharmacopeia (USP) Reference Standard, Chlorpropamide, Pharmaceutical Secondary Standard; Certified Reference Material
Drug Type	Small molecule
Formula	C₁₀H₁₃ClN₂O₃S
SMILES	CCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)Cl
InChI	1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)
InChIKey	RKWGIWYCVPQPMF-UHFFFAOYSA-N
CAS Number	94-20-2
ChEMBL ID	CHEMBL498
ChEBI ID	CHEBI:3650
TTD ID	D00BCP
Drug Bank ID	DB00672
KEGG ID	D00271
Toxicity	Organism	Test Type	Route(Dose)
	rat	LD50	intraperitoneal(165 mg/kg)
	mouse	LD50	intraperitoneal(254 mg/kg)
	rat	LD50	oral(322 mg/kg)
Structure			Download 2D MOL 3D MOL

Pair Name	Niacinamide, Chlorpropamide
Partner Name	Niacinamide
Result	The efficacy of insulin and other antidiabetic agents may be diminished by certain drugs, including atypical antipsychotics, corticosteroids, diuretics, estrogens, gonadotropin-releasing hormone agonists, human growth hormone, phenothiazines, progestins, protease inhibitors, sympathomimetic amines, thyroid hormones, L-asparaginase, alpelisib, copanlisib, danazol, diazoxide, isoniazid, megestrol, omacetaxine, phenytoin, tagraxofusp, temsirolimus, as well as pharmacologic dosages of nicotinic acid and adrenocorticotropic agents. These drugs may interfere with blood glucose control because they can cause hyperglycemia, glucose intolerance, new-onset diabetes mellitus, and/or exacerbation of preexisting diabetes.