Name | Stromal cell-derived factor 1 | ||
UniProt ID | SDF1_HUMAN | ||
Gene Name | CXCL12 | ||
Gene ID | 6387 | ||
Synonyms |
CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B
|
||
Sequence |
MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIV
ARLKNNNRQVCIDPKLKWIQEYLEKALNKRFKM |
||
Pathway Map | MAP LINK | ||
KEGG ID | hsa6387 | ||
TTD ID | T04773 | ||
Pfam | PF00048 |
Pair Name | Morin, Fludarabine | |||
Phytochemical | Morin | |||
Drug | Fludarabine | |||
Disease Info | [ICD-11: 2A82] | Chronic lymphocytic leukemia | Investigative | |
Regulate Info | Down-regulation | Stromal cell-derived factor 1 | Expression | |
Result | Morin treatment in CLL-derived Mec-1 cell line synergizes with conventional anticancer drugs currently used in CLL therapy by affecting leukemic cell viability and trafficking. |