
| Name | Stromal cell-derived factor 1 | ||
| UniProt ID | SDF1_HUMAN | ||
| Gene Name | CXCL12 | ||
| Gene ID | 6387 | ||
| Synonyms |
CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B
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| Sequence |
MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIV
ARLKNNNRQVCIDPKLKWIQEYLEKALNKRFKM |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa6387 | ||
| TTD ID | T04773 | ||
| Pfam | PF00048 | ||
| Pair Name | Morin, Fludarabine | |||
| Phytochemical | Morin | |||
| Drug | Fludarabine | |||
| Disease Info | [ICD-11: 2A82] | Chronic lymphocytic leukemia | Investigative | |
| Regulate Info | Down-regulation | Stromal cell-derived factor 1 | Expression | |
| Result | Morin treatment in CLL-derived Mec-1 cell line synergizes with conventional anticancer drugs currently used in CLL therapy by affecting leukemic cell viability and trafficking. | |||