| Name | Coxsackievirus and adenovirus receptor | ||
| UniProt ID | CXAR_HUMAN | ||
| Gene Name | CXADR | ||
| Gene ID | 1525 | ||
| Synonyms |
CXADR, CAR, CAR4/6, HCAR
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| Sequence |
MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLIS
PADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQC KVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSD SQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIA GAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHS SLGSMSPSNMEGYSKTQYNQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIPVMIPAQSK DGSIV |
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| Pathway Map | MAP LINK | ||
| T.C. Number | 8.A.23.1.14 | ||
| KEGG ID | hsa1525 | ||
| Pfam | PF00047; PF01034; PF05790; PF05808; PF07679; PF07686; PF13895; PF13927; PF14575; PF15069; PF21314 | ||
| Pair Name | Epifriedelanol, Doxorubicin | |||
| Phytochemical | Epifriedelanol | |||
| Drug | Doxorubicin | |||
| Disease Info | [ICD-11: 2B33.2] | Chronic myeloid leukemia | Investigative | |
| Regulate Info | Up-regulation | Coxsackievirus and adenovirus receptor | Expression | |
| Result | The present study demonstrated that Epi could enhance Adr-induced cytotoxicity towards K562/ADM cells accompanied by the down-regulation of P-gp and MRP2. | |||
