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  1. General Info
  2. Effects Info
  3. Reference
Molecular Details
01. General Information
Name Charged multivesicular body protein 1a
UniProt ID CHM1A_HUMAN
Gene Name CHMP1A
Gene ID 5119
Synonyms
CHMP1A, CHMP1, PCH8, PCOLN3, PRSM1, VPS46-1, VPS46A
Sequence
MDDTLFQLKFTAKQLEKLAKKAEKDSKAEQAKVKKALLQKNVECARVYAENAIRKKNEGV
NWLRMASRVDAVASKVQTAVTMKGVTKNMAQVTKALDKALSTMDLQKVSSVMDRFEQQVQ
NLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLSQLPEGASAVGESSV
RSQEDQLSRRLAALRN
Pathway Map MAP LINK
T.C. Number 3.A.31.1.2
KEGG ID hsa5119
Pfam PF03357; PF03398
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 418
Pair Name Anacardic Acid, Fluorouracil
Phytochemical Anacardic Acid
Drug Fluorouracil
Disease Info [ICD-11: 2C10] Pancreatic cancer Investigative
Regulate Info Up-regulation Charged multivesicular body protein 1a Expression
Result Our data suggests that Anacardic Acid might be a promising complementary supplement to slow the initiation or progression of pancreatic cancer.
03. Reference
No. Title Href
1 Anacardic acid inhibits pancreatic cancer cell growth, and potentiates chemotherapeutic effect by Chmp1A - ATM - p53 signaling pathway. BMC Complement Altern Med. 2018 Feb 20;18(1):71. doi: 10.1186/s12906-018-2139-3. Click
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