| Name | CCAAT/enhancer-binding protein beta | ||
| UniProt ID | CEBPB_HUMAN | ||
| Gene Name | CEBPB | ||
| Gene ID | 1051 | ||
| Synonyms |
CEBPB, C/EBP-beta, IL6DBP, NF-IL6, TCF5
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| Sequence |
MQRLVAWDPACLPLPPPPPAFKSMEVANFYYEADCLAAAYGGKAAPAAPPAARPGPRPPA
GELGSIGDHERAIDFSPYLEPLGAPQAPAPATATDTFEAAPPAPAPAPASSGQHHDFLSD LFSDDYGGKNCKKPAEYGYVSLGRLGAAKGALHPGCFAPLHPPPPPPPPPAELKAEPGFE PADCKRKEEAGAPGGGAGMAAGFPYALRAYLGYQAVPSGSSGSLSTSSSSSPPGTPSPAD AKAPPTACYAGAAPAPSQVKSKAKKTVDKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQ HKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPEPLLASSGHC |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa1051 | ||
| TTD ID | T10252 | ||
| Pfam | PF00170; PF03131; PF04977; PF06785; PF07716; PF08614; PF09728; PF11932; PF13874; PF15456; PF15799 | ||
| Pair Name | All-trans retinoic acid, Midostaurin | |||
| Phytochemical | All-trans-retinoic acid | |||
| Drug | Midostaurin | |||
| Disease Info | [ICD-11: 2A60.Z] | Acute myeloid leukemia | Investigative | |
| Regulate Info | Up-regulation | CCAAT/enhancer-binding protein beta | Expression | |
| Result | Combination of midostaurin and ATRA exerts dose-dependent dual effects on acute myeloid leukemia cells with wild type FLT3 | |||
