| Name | C-C chemokine receptor type 6 | ||
| UniProt ID | CCR6_HUMAN | ||
| Gene Name | CCR6 | ||
| Gene ID | 1235 | ||
| Synonyms |
CCR6, BN-1, C-C_CKR-6, CC-CKR-6, CCR-6, CD196, CKR-L3, CKRL3, CMKBR6, DCR2, DRY6, GPR29, GPRCY4, STRL22
|
||
| Sequence |
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKT LVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTV TEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQT SETADNDNASSFTM |
||
| Pathway Map | MAP LINK | ||
| KEGG ID | hsa1235 | ||
| TTD ID | T63165 | ||
| Pfam | PF00001 | ||
| Pair Name | Curcumin, TNF-related apoptosis inducing ligand | |||
| Phytochemical | Curcumin | |||
| Drug | TNF-related apoptosis inducing ligand | |||
| Disease Info | [ICD-11: 2C17] | Hepatocellular carcinoma | Investigative | |
| Regulate Info | Down-regulation | C-C chemokine receptor type 6 | Expression | |
| Result | The present study demonstrates the potential of using curcumin in combination with TRAIL to yield better TRAIL therapy outcomes in TRAIL-resistant CCA. | |||
| No. | Title | Href |
|---|---|---|
| 1 | Potentiation of TRAIL-Induced Apoptosis in TRAIL-Resistant Cholangiocarcinoma Cells by Curcumin through the Induction of DR5 Membrane Localization and Disruption of the Anti-Apoptotic Complex DR5/DDX3/GSK3β. Asian Pac J Cancer Prev. 2023 Feb 1;24(2):425-434. doi: 10.31557/APJCP.2023.24.2.425. | Click |
