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  1. General Info
  2. Effects Info
  3. Reference
Molecular Details
01. General Information
Name C-C motif chemokine 21
UniProt ID CCL21_HUMAN
Gene Name CCL21
Gene ID 6366
Synonyms
CCL21, 6Ckine, CKb9, ECL, SCYA21, SLC, TCA4
Sequence
MAQSLALSLLILVLAFGIPRTQGSDGGAQDCCLKYSQRKIPAKVVRSYRKQEPSLGCSIP
AILFLPRKRSQAELCADPKELWVQQLMQHLDKTPSPQKPAQGCRKDRGASKTGKKGKGSK
GCKRTERSQTPKGP
Pathway Map MAP LINK
KEGG ID hsa6366
TTD ID T93237
Pfam PF00048; PF20902
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 520
Pair Name Niacinamide, Gemcitabine
Phytochemical Niacinamide
Drug Gemcitabine
Disease Info [ICD-11: 2C10] Pancreatic cancer Investigative
Regulate Info Up-regulation C-C motif chemokine 21 Expression
Result This study highlights the potential of NAM+GEM as immunotherapy for advanced pancreatic cancer.
03. Reference
No. Title Href
1 Nicotinamide combined with gemcitabine is an immunomodulatory therapy that restrains pancreatic cancer in mice. J Immunother Cancer. 2020 Nov;8(2):e001250. doi: 10.1136/jitc-2020-001250. Click
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