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  1. General Info
  2. Effects Info
  3. Reference
Drug Details
01. General Information
Name BIBR1532
PubChem CID 9927531
Molecular Weight 331.4g/mol
Synonyms

BIBR 1532, 321674-73-1, BIBR1532, (E)-2-(3-(naphthalen-2-yl)but-2-enamido)benzoic acid, BIBR-1532, CHEMBL27323, 2-[[(E)-3-naphthalen-2-ylbut-2-enoyl]amino]benzoic Acid, 2-{[(2e)-3-(Naphthalen-2-Yl)but-2-Enoyl]amino}benzoic Acid, 2197129-84-1, 2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic acid, MLS006011127, SCHEMBL16964998, CHEBI:94985, DTXSID70432975, EX-A381, GLXC-03290, GLXC-25625, IBR 1532, WMA67473, Telomerase Inhibitor X, BIBR1532, BDBM50126186, MFCD11112195, s1186, AKOS024457366, CCG-264852, CS-0902, NCGC00242492-01, NCGC00242492-09, AC-26865, AS-56088, HY-17353, SMR004702907, SW219803-1, 2-(3-(Naphthalen-2-yl)but-2-enamido)benzoicacid, 2-(3-(Naphthalen-2-yl)but-2-enamido)benzoic acid, BRD-K04623885-001-01-8, Q27455481, 2-[(e)-3-naphthalen-2-yl-but-2-enoylamino]-benzoic acid, 55C

Drug Type Not Available
Formula C₂₁H₁₇NO₃
SMILES CC(=CC(=O)NC1=CC=CC=C1C(=O)O)C2=CC3=CC=CC=C3C=C2
InChI 1S/C21H17NO3/c1-14(16-11-10-15-6-2-3-7-17(15)13-16)12-20(23)22-19-9-5-4-8-18(19)21(24)25/h2-13H,1H3,(H,22,23)(H,24,25)/b14-12+
InChIKey PGFQXGLPJUCTOI-WYMLVPIESA-N
CAS Number 321674-73-1
ChEMBL ID CHEMBL27323
ChEBI ID CHEBI:94985
Toxicity Organism Test Type Route(Dose)
Structure 2D-img
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2D MOL 3D MOL
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 372
Pair Name Resveratrol, BIBR1532
Partner Name Resveratrol
Disease Info [ICD-11: 2B90] Colon cancer Investigative
Gene Regulation Down-regulation Expression CCAT1 KEGG ID N.A.
Down-regulation Expression CRNDE KEGG ID N.A.
Down-regulation Expression PCAT1 KEGG ID N.A.
Down-regulation Expression PVT1 KEGG ID N.A.
Down-regulation Expression SNHG16 KEGG ID N.A.
In Vitro Model HT-29 Colon adenocarcinoma Homo sapiens (Human) CVCL_0320
Result Resveratrol, BIBR1532, or their combination may have anti-proliferative effect on colorectal cancer cells through repressing expression of LncRNAs that are involved in progression of CRC.
03. Reference
No. Title Href
1 Combination of resveratrol and BIBR1532 inhibits proliferation of colon cancer cells by repressing expression of LncRNAs. Med Oncol. 2021 Nov 15;39(1):12. doi: 10.1007/s12032-021-01611-w. Click
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