| Name | Adenosine receptor A2a | ||
| UniProt ID | AA2AR_HUMAN | ||
| Gene Name | ADORA2A | ||
| Gene ID | 135 | ||
| Synonyms |
ADORA2A, A2aR, ADORA2, RDC8
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| Sequence |
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS |
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| Pathway Map | MAP LINK | ||
| T.C. Number | 9.A.14.3.8 | ||
| KEGG ID | hsa135 | ||
| TTD ID | T77365 | ||
| Pfam | PF00001; PF10320; PF10328; PF11970; PF13853 | ||
| Pair Name | Toosendanin, Paclitaxel | |||
| Phytochemical | Toosendanin | |||
| Drug | Paclitaxel | |||
| Disease Info | [ICD-11: 2C60] | Breast cancer | Investigative | |
| Regulate Info | Down-regulation | Adenosine receptor A2a | Expression | |
| Result | The results suggest that combination of TSN and PTX is superior to PTX alone, suggesting that it may be a promising alternative adjuvant chemotherapy strategy for patients with TNBC, especially those with metastatic TNBC. | |||
