Name | Low molecular weight phosphotyrosine protein phosphatase | ||
UniProt ID | PPAC_HUMAN | ||
Gene Name | ACP1 | ||
Gene ID | 52 | ||
Synonyms |
ACP1, HAAP, LMW-PTP, LMWPTP
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Sequence |
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRG
QSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSY DPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH |
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Pathway Map | MAP LINK | ||
KEGG ID | hsa52 | ||
Pfam | PF01451 |
Pair Name | Morin, Fludarabine | |||
Phytochemical | Morin | |||
Drug | Fludarabine | |||
Disease Info | [ICD-11: 2A82] | Chronic lymphocytic leukemia | Investigative | |
Regulate Info | Down-regulation | Low molecular weight phosphotyrosine protein phosphatase | Expression | |
Result | Morin treatment in CLL-derived Mec-1 cell line synergizes with conventional anticancer drugs currently used in CLL therapy by affecting leukemic cell viability and trafficking. |