研究成果

(8)Hong Y, Xu H, Liu Y, Zhu S, Tian C, Chen G, Zhu F, Tao L. DDID: a comprehensive resource for visualization and analysis of diet-drug interactions. Brief Bioinform . 2024 Mar 27;25(3):bbae212. DOI: 10.1093/bib/bbae212.

(7)Xu HQ, Xiao H, Bu JH, Hong YF, Liu YH, Tao ZY, Ding SF, Xia YT, Wu E, Yan Z, Zhang W, Chen GX, Zhu F, Tao L. EMNPD: a comprehensive endophytic microorganism natural products database for prompt the discovery of new bioactive substances. J Cheminform . 2023 Nov 28;15(1):115.DOI: 10.1186/s13321-023-00779-9.

(6)Xu H, Zhang W, Zhou Y, Yue Z, Yan T, Zhang Y, Liu Y, Hong Y, Liu S, Zhu F, Tao L. Systematic Description of the Content Variation of Natural Products (NPs): To Prompt the Yield of High-Value NPs and the Discovery of New Therapeutics. J Chem Inf Model . 2023 Mar 13;63(5):1615-1625.DOI: 10.1021/acs.jcim.2c01459.

(5)Hong J, Luo Y, Zhang Y, Ying J, Xue W, Xie T, Tao L ,Zhu F. Protein functional annotation of simultaneously improved stability, accuracy and false discovery rate achieved by a sequence-based deep learning.Brief Bioinform . 2020 Jul 15;21(4):1437-1447. DOI: 10.1093/bib/bbz081.

(4)Tao L. , Zhu F, Xu F, Chen Z, Jiang YY, Chen YZ. Co-targeting cancer drug escape pathways confers clinical advantage for multi-target anticancer drugs.Pharmacol Res . 2015 Dec;102:123-31.DOI: 10.1016/j.phrs.2015.09.019.

(3)Tao L. , Zhang P, Qin C, Chen SY, Zhang C, Chen Z, Zhu F, Yang SY, Wei YQ, Chen YZ. Recent progresses in the exploration of machine learning methods as in-silico ADME prediction tools.Adv Drug Deliv Rev . 2015 Jun 23;86:83-100.DOI: 10.1016/j.addr.2015.03.014.

(2)Tao L. , Zhu F, Qin C, Zhang C, Chen S, Zhang P, Zhang C, Tan C, Gao C, Chen Z, Jiang Y, Chen YZ. Clustered distribution of natural product leads of drugs in the chemical space as influenced by the privileged target-sites. Sci Rep . 2015 Mar 20;5:9325.DOI: 10.1038/srep09325.

(1)Tao L. , Zhu F, Qin C, Zhang C, Xu F, Tan CY, Jiang YY, Chen YZ. Nature's contribution to today's pharmacopeia. Nat Biotechnol . 2014 Oct;32(10):979-80.DOI: 10.1038/nbt.3034.

Database

· DDID: a comprehensive resource for visualization and analysis of diet–drug interactions

· EMNPD: Endophyte Mircoorganism Natural Product Database

· NPcVar: Natural Product Content Variations Database