5,7,4'-trihydroxy-3',5'-dimethoxy-flavone, 5,7,4'-trihydroxy-3',5'-dimethoxyflavone, tricin
| Name | Tricin | ||
| PubChem CID | 5281702 | ||
| Molecular Weight | 330.29g/mol | ||
| Synonyms |
5,7,4'-trihydroxy-3',5'-dimethoxy-flavone, 5,7,4'-trihydroxy-3',5'-dimethoxyflavone, tricin |
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| Formula | C₁₇H₁₄O₇ | ||
| SMILES | COC1=CC(=CC(=C1O)OC)C2=CC(=O)C3=C(C=C(C=C3O2)O)O | ||
| InChI | 1S/C17H14O7/c1-22-14-3-8(4-15(23-2)17(14)21)12-7-11(20)16-10(19)5-9(18)6-13(16)24-12/h3-7,18-19,21H,1-2H3 | ||
| InChIKey | HRGUSFBJBOKSML-UHFFFAOYSA-N | ||
| CAS Number | 520-32-1 | ||
| ChEMBL ID | CHEMBL454320 | ||
| ChEBI ID | CHEBI:59979 | ||
| Herb ID | HBIN046960 | ||
| KEGG ID | C10193 | ||
| Structure | 
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2D
MOL
3D
MOL
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| Chineses Pinyin | XiaoMai | ||
| Use Part | Seed | ||
| Habitat | China | ||
| Flavor | Sweet | ||
| Meridian Tropism | Spleen; Heart; Kidney | ||
| Species |
>Kingdom: Viridiplantae
-->Phylum: Streptophyta
-->Class: Equisetopsida
-->Order: Poales
-->Family: Poaceae
-->Genus: Triticum
-->Species: Triticum aestivum
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| Pair Name | Tricin, Docetaxel | |||
| Partner Name | Docetaxel | |||
| Disease Info | [ICD-11: 2C82] | Prostate cancer | Investigative | |
| Biological Phenomena | Inhibition-->Cell proliferation | |||
| Gene Regulation | Down-regulation | Expression | MiR-21 | KEGG ID N.A. |
| In Vitro Model | PC-3 | Prostate carcinoma | Homo sapiens (Human) | CVCL_0035 |
| Result | Tricin can be effective in the reduction of metastasis and drug resistance of Docetaxel. | |||
