| Name | Tubulin beta-3 chain | ||
| UniProt ID | TBB3_HUMAN | ||
| Gene Name | TUBB3 | ||
| Gene ID | 10381 | ||
| Synonyms |
TUBB3, CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4
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| Sequence |
MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV
PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS EYQQYQDATAEEEGEMYEDDEEESEAQGPK |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa10381 | ||
| Pfam | PF00091; PF03953; PF10644; PF13809; PF14881 | ||
| Pair Name | Phorbol 12-myristate 13-acetate, Apicularen A | |||
| Phytochemical | Phorbol 12-myristate 13-acetate | |||
| Drug | Apicularen A | |||
| Disease Info | [ICD-11: 2C77] | Cervical cancer | Investigative | |
| Regulate Info | Down-regulation | Tubulin beta-3 chain | Expression | |
| Result | These results suggest that the synergy between PMA and apicularen A is involved by PKCα activation and microtubule disruption, and that may inform the development of novel approaches to treat cancer. | |||
