| Name | Tubulin alpha-1B chain | ||
| UniProt ID | TBA1B_HUMAN | ||
| Gene Name | TUBA1B | ||
| Gene ID | 10376 | ||
| Synonyms |
TUBA1B, K-ALPHA-1
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| Sequence |
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPP TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE AREDMAALEKDYEEVGVDSVEGEGEEEGEEY |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa10376 | ||
| TTD ID | T70119 | ||
| Pfam | PF00091; PF03953; PF14881 | ||
| Pair Name | Phorbol 12-myristate 13-acetate, Apicularen A | |||
| Phytochemical | Phorbol 12-myristate 13-acetate | |||
| Drug | Apicularen A | |||
| Disease Info | [ICD-11: 2C77] | Cervical cancer | Investigative | |
| Regulate Info | Down-regulation | Tubulin alpha-1B chain | Expression | |
| Result | These results suggest that the synergy between PMA and apicularen A is involved by PKCα activation and microtubule disruption, and that may inform the development of novel approaches to treat cancer. | |||
