| Pair Name | Sinomenium acutum, Cisplatin | ||
| Phytochemical Name | Sinomenium acutum (PubChem CID: 5459308 ) | ||
| Anticancer drug Name | Cisplatin (PubChem CID: 5702198 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Sinomenium acutum, Cisplatin | |||
| Disease Info | [ICD-11: 2C25] | Lung cancer | Investigative | |
| Gene Regulation | Down-regulation | Expression | MIR200A | hsa406983 |
| In Vitro Model | A-549 | Lung adenocarcinoma | Homo sapiens (Human) | CVCL_0023 |
| Result | This study revealed a new molecular mechanism for the sinomenine-promoted cisplatin sensitization, contributing to investigating the sinomenine-based therapeutic agents against chemoresistant NSCLC. | |||
| No. | Title | Href |
|---|---|---|
| 1 | Overcoming cisplatin resistance of human lung cancer by sinomenine through targeting the miR-200a-3p-GLS axis. J Chemother. 2023 Jul;35(4):357-366. doi: 10.1080/1120009X.2022.2111490. | Click |
