| Name | AMSH-like protease | ||
| UniProt ID | STALP_HUMAN | ||
| Gene Name | STAMBPL1 | ||
| Gene ID | 57559 | ||
| Synonyms |
STAMBPL1, ALMalpha, AMSH-FP, AMSH-LP, bA399O19.2
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| Sequence |
MDQPFTVNSLKKLAAMPDHTDVSLSPEERVRALSKLGCNITISEDITPRRYFRSGVEMER
MASVYLEEGNLENAFVLYNKFITLFVEKLPNHRDYQQCAVPEKQDIMKKLKEIAFPRTDE LKNDLLKKYNVEYQEYLQSKNKYKAEILKKLEHQRLIEAERKRIAQMRQQQLESEQFLFF EDQLKKQELARGQMRSQQTSGLSEQIDGSALSCFSTHQNNSLLNVFADQPNKSDATNYAS HSPPVNRALTPAATLSAVQNLVVEGLRCVVLPEDLCHKFLQLAESNTVRGIETCGILCGK LTHNEFTITHVIVPKQSAGPDYCDMENVEELFNVQDQHDLLTLGWIHTHPTQTAFLSSVD LHTHCSYQLMLPEAIAIVCSPKHKDTGIFRLTNAGMLEVSACKKKGFHPHTKEPRLFSIC KHVLVKDIKIIVLDLR |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa57559 | ||
| Pfam | PF01398; PF08969; PF14464 | ||
| Pair Name | Tubeimoside I, TNF-related apoptosis inducing ligand | |||
| Phytochemical | Tubeimoside I | |||
| Drug | TNF-related apoptosis inducing ligand | |||
| Disease Info | [ICD-11: 2A00-2F9Z] | Solid tumour or cancer | Investigative | |
| Regulate Info | Down-regulation | AMSH-like protease | Expression | |
| Result | Our study revealed that STAMBPL1 is essential for c-FLIP stabilization, and that STAMBPL1 depletion enhances TRAIL-mediated apoptosis via c-FLIP downregulation. | |||
