| Name | Retinoic acid receptor alpha | ||
| UniProt ID | RARA_HUMAN | ||
| Gene Name | RARA | ||
| Gene ID | 5914 | ||
| Synonyms |
RARA, NR1B1, RAR, RARalpha
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| Sequence |
MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPAT
IETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTV EFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA GFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALK VYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGL DTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP |
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| Pathway Map | MAP LINK | ||
| T.C. Number | 1.A.14.1.1; 1.A.14.3.3; 1.A.14.3.6; 1.C.46.1.2; 2.A.17.2.3 | ||
| KEGG ID | hsa5914 | ||
| TTD ID | T94085 | ||
| Pfam | PF00104; PF00105 | ||
| Pair Name | All-trans retinoic acid, Decitabine | |||
| Phytochemical | All-trans-retinoic acid | |||
| Drug | Decitabine | |||
| Disease Info | [ICD-11: 2A60.Z] | Acute myeloid leukemia | Investigative | |
| Regulate Info | Up-regulation | Retinoic acid receptor alpha | Activity | |
| Result | These results demonstrate that combining DAC and ATRA has potential for the clinical treatment of HR-MDS/AML and merits further exploration. | |||
