| Name | Ras-related C3 botulinum toxin substrate 3 | ||
| UniProt ID | RAC3_HUMAN | ||
| Gene Name | RAC3 | ||
| Gene ID | 5881 | ||
| Synonyms |
RAC3
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| Sequence |
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLR DDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPP PVKKPGKKCTVF |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa5881 | ||
| TTD ID | T06525 | ||
| Pfam | PF00009; PF00025; PF00071; PF08477 | ||
| Pair Name | Pulsatilla saponin D, Paclitaxel | |||
| Phytochemical | Pulsatilla saponin D | |||
| Drug | Paclitaxel | |||
| Disease Info | [ICD-11: 2C25.Z] | Lung cancer | Investigative | |
| Regulate Info | Down-regulation | Ras-related C3 botulinum toxin substrate 3 | Expression | |
| Result | We found that treatment with paclitaxel combined with Pulsatilla saponin D, can overcome lung adenocarcinoma cell resistance to paclitaxel alone in cell culture and mouse xenograft models. | |||
