Pair Name	Paeonol, Paclitaxel
Disease Info	[ICD-11: 2C60]	Breast cancer		Investigative
Gene Regulation	Down-regulation	Expression	transgelin 2	KEGG ID N.A.
	Down-regulation	Expression	P-gp	KEGG ID N.A.
	Down-regulation	Expression	MRP1	KEGG ID N.A.
	Down-regulation	Expression	BCRP	KEGG ID N.A.
In Vitro Model	MCF-7/PTX	Invasive breast carcinoma of no special type	Homo sapiens (Human)	CVCL_C5RS
Result	These results not only provide insight into the potential application of paeonol to the reversal of paclitaxel resistance, thus facilitating the sensitivity of breast cancer chemotherapy, but also highlight a potential role of transgelin 2 in the development of paclitaxel resistance in breast cancer.