Name | Astrocytic phosphoprotein PEA-15 | ||
UniProt ID | PEA15_HUMAN | ||
Gene Name | PEA15 | ||
Gene ID | 8682 | ||
Synonyms |
PEA15, HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED, PED-PEA15, PED/PEA15
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Sequence |
MAEYGTLLQDLTNNITLEDLEQLKSACKEDIPSEKSEEITTGSAWFSFLESHNKLDKDNL
SYIEHIFEISRRPDLLTMVVDYRTRVLKISEEDELDTKLTRIPSAKKYKDIIRQPSEEEI IKLAPPPKKA |
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Pathway Map | MAP LINK | ||
KEGG ID | hsa8682 | ||
Pfam | PF01335 |
Pair Name | Epigallocatechin gallate, TNF-related apoptosis inducing ligand | |||
Phytochemical | Epigallocatechin gallate | |||
Drug | TNF-related apoptosis inducing ligand | |||
Disease Info | [ICD-11: 2A00] | Glioblastoma multiforme | Investigative | |
Regulate Info | Down-regulation | Astrocytic phosphoprotein PEA-15 | Expression | |
Result | Epigalocatechin-3-gallate (EGCG) downregulates PEA15 and thereby augments TRAIL-mediated apoptosis in malignant glioma |