Pair Name	Nicotinic acid, Copper (I)
Disease Info	[ICD-11: 2C60]	Breast cancer		Investigative
Biological Phenomena	Induction-->Autophagy
Gene Regulation	Down-regulation	Expression	MAP1LC3A	hsa84557
	Up-regulation	Expression	NBR1	hsa4077
In Vitro Model	HCC1806	Breast squamous cell carcinoma, acantholytic variant	Homo sapiens (Human)	CVCL_1258
	MDA-MB-231	Breast adenocarcinoma	Homo sapiens (Human)	CVCL_0062
Result	CNC restrained the growth, in a dose-dependent manner, and induced cell death in human HCC1806 cell line. In addition, the CNC treated cells displayed inhibition of autophagy, as indicated by reduction of AVOs, decrease in LC3 protein level and up regulation of NBR1 gene expression.