Name | Dehydrodolichyl diphosphate synthase complex subunit NUS1 | ||
UniProt ID | NGBR_HUMAN | ||
Gene Name | NUS1 | ||
Gene ID | 116150 | ||
Synonyms |
NUS1, C6orf68, CDG1AA, MGC:7199, MRD55, NgBR, TANGO14
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Sequence |
MTGLYELVWRVLHALLCLHRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPP
AVGRNRRHHRHPRGGSCLAAAHHRMRWRADGRSLEKLPVHMGLVITEVEQEPSFSDIASL VVWCMAVGISYISVYDHQGIFKRNNSRLMDEILKQQQELLGLDCSKYSPEFANSNDKDDQ VLNCHLAVKVLSPEDGKADIVRAAQDFCQLVAQKQKRPTDLDVDTLASLLSSNGCPDPDL VLKFGPVDSTLGFLPWHIRLTEIVSLPSHLNISYEDFFSALRQYAACEQRLGK |
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Pathway Map | MAP LINK | ||
KEGG ID | hsa116150 | ||
Pfam | PF01255 |
Pair Name | Artesunate, Sorafenib | |||
Phytochemical | Artesunate | |||
Drug | Sorafenib | |||
Disease Info | [ICD-11: 2C12] | Hepatocellular carcinoma | Investigative | |
Regulate Info | Down-regulation | Dehydrodolichyl diphosphate synthase complex subunit NUS1 | Expression | |
Result | We report that sorafenib treatment in combination with artesunate overcomes HCC resistance to sorafenib alone in a cell culture model. |