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  1. General Info
  2. Effects Info
  3. Reference
Molecular Details
01. General Information
Name MicroRNA 301a
UniProt ID /
Gene Name MIR301A
Gene ID 407027
Synonyms
MIR301A, MIR301, MIRN301, MIRN301A, mir-301a
Sequence
/
Pathway Map MAP LINK
KEGG ID hsa407027
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 408
Ref_1
Pair Name Luteolin, TNF-related apoptosis inducing ligand
Phytochemical Luteolin
Drug TNF-related apoptosis inducing ligand
Disease Info [ICD-11: 2C10.Z] Pancreatic cancer Investigative
Regulate Info Down-regulation MicroRNA 301a Expression
Result Our findings unveil a critical biological function of miR-301-3p in regulating cell proliferation and elevating an antiproliferative effect of TRAIL on cancer cells. Our observation of miR-301-3p/caspase-8 relationship can also serve to clarify the role of miR-301-3p in other cancer types and related diseases.
03. Reference
No. Title Href
1 Luteolin-regulated MicroRNA-301-3p Targets Caspase-8 and Modulates TRAIL Sensitivity in PANC-1 Cells. Anticancer Res. 2020 Feb;40(2):723-731. doi: 10.21873/anticanres.14003. Click
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