| Name | Dual specificity mitogen-activated protein kinase kinase 3 | ||
| UniProt ID | MP2K3_HUMAN | ||
| Gene Name | MAP2K3 | ||
| Gene ID | 5606 | ||
| Synonyms |
MAP2K3, MAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2
|
||
| Sequence |
MESPASSQPASMPQSKGKSKRKKDLRISCMSKPPAPNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHL HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD FTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS |
||
| Pathway Map | MAP LINK | ||
| KEGG ID | hsa5606 | ||
| Pfam | PF00069; PF01163; PF01633; PF01636; PF03109; PF07387; PF07714; PF12330; PF14247; PF14531 | ||
| Pair Name | Usnic acid, Sorafenib | |||
| Phytochemical | Usnic acid | |||
| Drug | Sorafenib | |||
| Disease Info | [ICD-11: 2C12] | Hepatocellular carcinoma | Investigative | |
| Regulate Info | Down-regulation | Dual specificity mitogen-activated protein kinase kinase 3 | Expression | |
| Result | Investigation of new treatment option for hepatocellular carcinoma: a combination of sorafenib with usnic acid | |||
