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General Info
Effects Info
Antagonistic
Reference
Drug Details
01. General Information
Name
Inhibit UGT1A1-mediated bilirubin glucuronidation
Drug Type
Not Available
Toxicity
Organism
Test Type
Route(Dose)
Structure
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2D MOL
3D MOL
02. Combinatorial Therapeutic Effect(s)
Antagonistic Effect
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Enhancing Drug Toxicity
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Combination Pair ID: 1084
Ref_1
Pair Name
Rosmarinic acid, Inhibit UGT1A1-mediated bilirubin glucuronidation
Partner Name
Rosmarinic acid
Result
Jaundice; hyperbilirubinemia
03. Reference
No.
Title
Href
1
Inhibition of Human UGT1A1-Mediated Bilirubin Glucuronidation by Polyphenolic Acids Impact Safety of Popular Salvianolic Acid A/B-Containing Drugs and Herbal Products. Mol Pharm. 2017;14(9):2952-2966. doi:10.1021/acs.molpharmaceut.7b00365
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