| Name | Integrin beta-3 | ||
| UniProt ID | ITB3_HUMAN | ||
| Gene Name | ITGB3 | ||
| Gene ID | 3690 | ||
| Synonyms |
ITGB3, BDPLT16, BDPLT2, BDPLT24, CD61, GP3A, GPIIIa, GT, GT2
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| Sequence |
MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLG
SPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRP DDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFG AFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSR NRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCH VGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLS MDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDT VSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGT FECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFG KITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLL CSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRY CRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDIL VVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTF TNITYRGT |
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| Pathway Map | MAP LINK | ||
| T.C. Number | 1.C.74.1.9; 4.C.1.1.21 | ||
| KEGG ID | hsa3690 | ||
| TTD ID | T26457 | ||
| Pfam | PF00362; PF07965; PF07974; PF08725; PF17205; PF18372 | ||
| Pair Name | Juglone, Sodium selenite | |||
| Phytochemical | Juglone | |||
| Drug | Sodium selenite | |||
| Disease Info | [ICD-11: 2C10] | Pancreatic cancer | Investigative | |
| Regulate Info | Down-regulation | Integrin beta-3 | Expression | |
| Result | The juglone-NaSe has the potential to be a promising agent especially to inhibit invasion and metastasis in pancreatic cancer treatment. However, more in depth studies are needed to more clearly demonstrate the effects of juglone-selenium. | |||
| Pair Name | Juglone, Sodium selenite | |||
| Phytochemical | Juglone | |||
| Drug | Sodium selenite | |||
| Disease Info | [ICD-11: 2C10] | Pancreatic cancer | Investigative | |
| Regulate Info | Up-regulation | Integrin beta-3 | Expression | |
| Result | The juglone-NaSe has the potential to be a promising agent especially to inhibit invasion and metastasis in pancreatic cancer treatment. However, more in depth studies are needed to more clearly demonstrate the effects of juglone-selenium. | |||
| No. | Title | Href |
|---|---|---|
| 1 | The effects of Juglone-Selenium combination on invasion and metastasis in pancreatic cancer cell lines. Afr Health Sci. 2022 Jun;22(2):334-342. doi: 10.4314/ahs.v22i2.37. | Click |
| 2 | The effects of Juglone-Selenium combination on invasion and metastasis in pancreatic cancer cell lines. Afr Health Sci. 2022 Jun;22(2):334-342. doi: 10.4314/ahs.v22i2.37. | Click |
