| Name | Interleukin-12 subunit alpha | ||
| UniProt ID | IL12A_HUMAN | ||
| Gene Name | IL12A | ||
| Gene ID | 3592 | ||
| Synonyms |
IL12A, CLMF, IL-12A, NFSK, NKSF1, P35
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| Sequence |
MWPPGSASQPPPSPAAATGLHPAARPVSLQCRLSMCPARSLLLVATLVLLDHLSLARNLP
VATPDPGMFPCLHHSQNLLRAVSNMLQKARQTLEFYPCTSEEIDHEDITKDKTSTVEACL PLELTKNESCLNSRETSFITNGSCLASRKTSFMMALCLSSIYEDLKMYQVEFKTMNAKLL MDPKRQIFLDQNMLAVIDELMQALNFNSETVPQKSSLEEPDFYKTKIKLCILLHAFRIRA VTIDRVMSYLNAS |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa3592 | ||
| TTD ID | T13251 | ||
| Pfam | PF03039 | ||
| Pair Name | Quercetin, Anti-PD-1 antibody | |||
| Phytochemical | Quercetin | |||
| Drug | Anti-PD-1 antibody | |||
| Disease Info | [ICD-11: 2C12] | Hepatocellular carcinoma | Investigative | |
| Regulate Info | Down-regulation | Interleukin-12 subunit alpha | Expression | |
| Result | Quercetin/anti-PD-1 antibody combination therapy reshaped HCC tumor microenvironment in mice in parallel with regulating the GM and macrophage immunity. | |||
