| Name | Glutathione S-transferase theta-1 | ||
| UniProt ID | GSTT1_HUMAN | ||
| Gene Name | GSTT1 | ||
| Gene ID | 2952 | ||
| Synonyms |
GSTT1
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| Sequence |
MGLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDG
DFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMF PVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMHPVGA GCQVFEGRPKLATWRQRVEAAVGEDLFQEAHEVILKAKDFPPADPTIKQKLMPWVLAMIR |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa2952 | ||
| Pfam | PF00043; PF02798; PF13409; PF13410; PF13417; PF14497; PF17172 | ||
| Pair Name | Fucoxanthin, Doxorubicin | |||
| Phytochemical | Fucoxanthin | |||
| Drug | Doxorubicin | |||
| Disease Info | [ICD-11: 2C12] | Hepatocellular carcinoma | Investigative | |
| Regulate Info | Down-regulation | Glutathione S-transferase theta-1 | Activity | |
| Result | The carotenoid fucoxanthin can sensitize multidrug resistant cancer cells to doxorubicin via induction of apoptosis, inhibition of multidrug resistance proteins and metabolic enzymes | |||
